Renal failure reasons of high serum creatinin

The human body renal reserve capacity, the person's kidney more than 75% of the kidney unit does not work properly, creatinine high symptoms will be revealed. That is, man's kidney hurt haven't reached the level, creatinine still is normal. So in the kidney damage in the later stage of the serum creatinine can have the clinical significance
The reasons of high serum creatinine, kidney failur
Creatinine is one of the body's metabolism product, and the main creatine generation. Creatine can for our body muscle activities with energy. As long as muscle activity will consume energy generation creatinine. But creatinine constantly produce, the excessive accumulation in the body of the body to produce poisonous effect. By constantly need glomerular filtration urine from the body from the bodies
Second, renal failure reasons of high serum creatinin
When normal renal function, creatinine glomerular filter from urine from the tossed out. Renal damage, creatinine from kidney row not to go out, but after intestinal waste eliminated from the body. Normally produced in the body of the speed of 1 serum creatinine mg/minutes, glomerular also at the same speed put it cleared away. When kidney function decline to certain degree, the blood creatinine can rise, but when compensatory mechanism normal renal function, blood creatinine increased also can appear
When left normal renal function of the three points at that time, the kidney compensatory, blood creatinine increased only, so blood creatinine and not sensitivity of glomerular filtration function index. The normal serum creatinine is 40-120 umol/L, muscle atrophy, thin body, factors such as pregnancy can make creatinine slightly low. Opinion, creatinine indicators and was not accurate in reflecting the stand or fall of renal function
Cause kidney damage of all kinds of primary, secondary kidney disease farming, or the lack of early detection, can make patients finally appears creatinine high symptoms. And from the point of view of the pathological and histological, kidney function by different kinds of pathogenic factors cells influence, by the steady injury, necrosis, also can saying is the cause of the high serum creatinine