Are You Still Suffering from Nephrotic Syndrome and High Creatinine

Nephrotic Syndrome is a nonspecific disorder in which the kidneys are damaged, causing them to leak large amounts of protein (proteinuria at least 3.5 grams per day per 1.73m2 body surface area) from the blood into the urine. Besides proteinuria, swelling and hyperlipidemia are also the common symptoms of Nephrotic Syndrome. However, can Nephrotic Syndrome patients have high creatinine?Are You Still Suffering from Nephrotic Syndrome and High Creatinine?
Yes, the answer is definite. Nephrotic syndrome is usually caused by damage to the clusters of tiny blood vessels (glomeruli) of your kidneys. So once there is something wrong with glomeruli, the creatinine and other toxins can not be fully filtered out of body, they will accumulate in the body, so it is very common that high creatinine appears in Nephrotic Syndrome patients.
If wanting to lower high creatinine, we should begin with the reason causing Nephrotic Syndrome. We have mentioned above, the damaged glomeruli is the key. We must repair and recover the function of glomeruli. Unlike the common treatments, they just focus on improving symptoms rather than repair the damaged kidney itself. In that case, even though some symptoms can be controlled, the condition will also reappear, which is because that the root cause has not been solved.
According to this issue, we recommend Micro-Chinese Medicine Osmotherapy to lower creatinine and treat Nephrotic Syndrome. Micro-Chinese Medicine Osmotherapy is a natural herbal therapy applied externally on acupoint of lower back (kidney area). With the help of osmosis device, effective ingredients of herbal medicines will infiltrate into kidneys through the main and channels. There is no pain, and it is kind of like a massage.
If at the early stage of Nephrotic Syndrome, Micro-Chinese Medicine Osmotherapy is able to treat it, and the prognosis will be good. If the condition develops into Renal Failure, maybe Biological Immunotherapy will be needed to cooperate Micro-Chinese Medicine Osmotherapy, so it will cost you much. As long as the function of glomeruli is repaired, creatinine level will come back to the normal level, as well as other symptoms will be improved naturally.

Why creatinine increases nephrotic syndrome?

Serum creatinine surface high reason of kidney damage kidneys cannot micturition, essence and serum creatinine high is caused by kidney in the various causes of infringement by kidney cells after inherent damaged, happen fibrosis. First the damaged kidney cell had phenotype inherent transformation, form the pathological changes, stimulate in kidney fibroblasts into muscle fibroblasts, and at the same time and inspired the infringement inherent normal kidney tissues, the same lesions occur, thus creating the kidney transference, from part to the overall, and expand the spread of JiFaShi process, thus into the quality of the damage (namely renal damage period), at this time due to damage to the kidney continuously, the discharge waste function decrease, created the toxin in the body, creatinine gathered themselves together, and thus appear in blood serum creatinine, urea nitrogen increases, urine creatinine drop, double kidney filtration rate, etc. At the same time patients will have high blood pressure, high swelling and other body other symptoms.
Why creatinine increases nephrotic syndrome? Is due to kidney in the various causes of infringement by, first the damaged kidney cell had phenotype inherent transformation, form the pathological changes, stimulate in kidney fibroblasts into muscle fibroblasts, and at the same time and inspired the infringement inherent normal kidney tissues, the same lesions occur, thus creating the kidney transference, from part to the overall, and expand the spread of JiFaShi process, thus into the quality of the damage (namely renal damage period), at this time due to damage to the kidney continuously, the discharge waste function decrease, created the toxin in the body, creatinine gathered themselves together, and thus appear in blood serum creatinine, urea nitrogen increases, urine creatinine drop, double kidney filtration rate, etc. At the same time patients will have high blood pressure, high swelling and other body other symptoms.

Pay Attention to the Proteinuria of Nephrotic Syndrome in Children

Nephrotic Syndrome in children is a common disease and the lots of proteinuriais one of the common symptoms. If the proteinuria can not be eliminated for a long time, the condition will become worse and worse. In that case, Renal Failure or Uremia may finally appear.
Why can protein appear in the urine? Generally speaking, the healthy people have no or little protein in our urine, once the kidney function is damaged and the glomerular filtration function is damaged, the protein will come into the urine, so proteinuria appears. The manifestation is the bubbles in urine. However, not all the bubbles in urine is related to kidney disease. The physiological proteinuria includes: child takes too much protein; too much and strenuous exercise; colds or urinary tract infections; the speed or angle when urinating and so on. Parents need not worry about physiological proteinuria, for it can disappear within short time. However, if proteinuria lasts for a long time, parents should find out whether it is caused by Nephrotic Syndrome or whether the Nephrotic Syndrome has been aggravated.
As to the treatment for proteinuria, hormone drugs is often used in clinical and people can see the obvious treatment effect. However, kidney damage has already existed and hormone drugs does nothing to the protection and repairing of kidney function. Also long-term use of hormone drugs has lots of side effects, for example, it will cause child grows slowly and affect his fertility and so on. Compared to the treatments of other hospital, we recommend you Chinese medicine, which can decrease the side effects of hormone drugs, and the most important is that Chinese medicine can protect and repair the damaged kidney tissues. Micro-Chinese Medicine Osmotherapy and medicated bath are two forms we usually use. They can eliminate the immune complexes and other toxins through promoting blood circulation and removing blood stasis, and the active materials of Chinese medicine can repair the damaged kidney tissues, however, it needs time, but very efficient and completely. As long as the kidney function is repaired, proteinuria and other symptoms of Nephrotic Syndrome can disappear naturally.

How to treat Kidney Disease in children with Nephrotic Syndrome has a little pain?

How to treat Kidney Disease in children with Nephrotic Syndrome has a little pain? Children in illness, popular in general need drug use. Because children have to take a combination of general diuresis hormonal drugs, child urine output increases, need special attention to teachers, class or activities timely remind children to go to the toilet, so as not to give a child unnecessary pain and suffering. Children with nephrotic syndrome because of protein in the urine from lost, the body's immune protein also constantly with the urine, the body drop, use a great number of hormone, more reduce immunity, and all kinds of infections extremely easily, cause illness relapses. Should make protective isolation, and children of the infection separated room, still should ask the propaganda maintain indoor air fresh, reduce visit personnel and stay in the hospital with her staff the importance of the medical ready to help guide of children's life care, in order to strengthen the protection ability.
Because a lot of protein to children with nephrotic syndrome from feces has been established since childhood, in body, often happen protein deficiency, reason should be given in the diet supplement. In addition, still should limit salt intake, generally not more than 2 grams per day. Specific parents can according to the patient's condition set up reasonable diet, and change often food color and type, meet the patient's eating habits, and encourage cooperate actively with children. In severe swelling, protein period should give no salt, low protein diet, in edema, oliguria period should limit their intake of protein.
For long-term use of hormone children, loss of immunity, easy to concurrent respiratory infections, should be strictly restricted the movements of the children. Can do some quiet game, avoid strenuous exercise, lest the child fatigue, worse. Parents should depending on weather changes to increase or decrease in children clothes, pay attention to keep warm. When siesta should give more concern, make sure your child plenty of sleep. Set up reasonable life system, in addition of appropriate edema rest in bed outside, try to keep children normal life and study, make children spirits. At the same time, increase or decrease gown in time, avoid to personnel densely populated, lest catch cold catch cold and cross infection.

In the dangers of proteinuria nephrotic syndrome

For patients with nephrotic syndrome, it proteinuria is a clear signs of it, but in the long run if the state and not the timely treatment for words, will produce a lot of adverse impact, so the patient to understand in the dangers of proteinuria nephrotic syndrome, early treatment and control albuminuria, reduce the hazards.
A, children's
For children with nephrotic syndrome, it will lead to long-term proteinuria hypoalbuminemia, had hypoalbuminemia will lead to malnutrition, cause of child growth slow, go against the body of children development. This is in the dangers of proteinuria nephrotic syndrome is one.
Second, infection
Because a large number of proteinuria in patients with lost immunoglobulin, and make the body's immune globulin is reduced, this will increase the risk of infection patients, and infections can cause kidney disease syndrome has increased.
Three, lack of trace elements
Kidney disease syndrome patients not only in the urine, lost a lot of protein, some trace elements with the protein in the urine and run, leading to the human body metabolism of trace elements needed for lack of, affect the body's metabolism.
Four, blood clots
Due to the loss of protein, leading to a tall lipemia and increased the clotting of blood, and cause blood clots, embolism, complications, and also may increase cardiovascular system complications, lead to illness.
In addition in the dangers of proteinuria nephrotic syndrome and can lead to the endocrine disorder, the influence of the drug treatment effect, so the patient should be timely treatment, avoid to produce harm in serious condition.

Cause nephrotic syndrome of proteinuria is the cause of the patients?

Kidney disease syndrome patients in a large number of protein in the urine is mainly derived from blood. Normally, nephrotic syndrome patients most of the blood protein is appearing in the urine, especially macromolecular proteins, as well as the negatively charged protein will not appear, this is because human kidney of glomerular filtration barrier being that the protein filtered out.

(1) is the endothelial cells lining blood capillary. Endothelial cells, there are many a diameter of 50-100 nm holes, so called window holes. Water, all kinds of solute and larger proteins can freely through the hole is; But can stop the passage of the blood cells, blood cells play the role of the barrier.

(2) the middle is the basement membrane of cells, a tiny fiber network structures. Plasma larger molecules substances, such as protein can't through the basement membrane. The film is to prevent the larger proteins glomerular filtration of the main barrier.

(3) outer layer is the epithelial cells of the glomerulus. The epithelial cells have foot processes, interlaced formed between foot processes of fractures. The fracture has a layer of filtration fissure diaphragm, membrane have 4-14 of nm diameter hole, it can stop by inside, two layer filter out of macromolecular proteins through, is a barrier at the end of the filter. Endothelial cells, the basement membrane and epithelial cells was composed of glomerular filtration membrane. Filtration membrane size different filtration, both can only make small molecules easily through, and the effective radius larger material can only be through the larger, both in general, effective radius is less than 1.8 nm substance, can be fully filtration. Effective radius of more than 3.6 nm macromolecular substances, such as plasma albumin (molecular weight of about 69000) are almost completely can't filtration.

What can lead to nephrotic syndrome proteinuria form

The emergence of the urinary protein, there may be a means of human kidney problems, so usually, a lot of people through the normal amount of urinary protein to determine whether the body health. Normally, for albuminuria, it may be possible to human kidney problems.
The kidney pathological changes of the renal fibrosis is called, is the latest theory with the current kidney disease. At present the renal fibrosis medical process is divided into three periods, namely the inflammatory lesions stage (induced phase), inflammation matrix formation, fibrosis scar formation. A lot of proteinuria happen throughout the kidney process fibrosis, is mainly because kidney was destroyed, filtration barrier basement membrane aperture expanding or fracture, and lead to protein leaks out. In the start stage renal fibrosis, i.e., inflammatory lesions stage, because all kinds of infections in the body self adjusting mechanism function disorder, generate different immune complex, and then these immune complex deposition in the different natural cell zone. These immune complex deposition, they will attract within the body of different types of inflammatory mediators, inflammatory mediators and immune complex a union, will lead to a variety of types of inflammation, these inflammatory response will stimulate the kidney cells, the inherent cells in sedimentary destruction damage.
When kidney function cells are damaged, can cause kidney local microcirculation, organization will cause a series of oxygen for ischemia and inflammation, and then further damage the kidneys inherent cells. Kidney cells damaged produce inflammation response once, glomerular local will appear "high filtration, high perfusion, high pressure inside the" three tenors symptoms, glomerular local will have pathological changes, such as the mesangium cell hyperplasia, membrane matrix is increasing, the basement membrane filtration aperture increase or closure, or the basement membrane rupture, charge barrier damage, these changes, glomerular filtration function is reduced, permeability increase.

How to distinguish between nephrotic syndrome

For reasons unknown primary nephrotic syndrome, must do to renal biopsy definitive diagnosis. The old membranous nephropathy, focal segmental venereal change is higher, the teenagers lesions and tiny lesions, a slight iga kidney disease and capillary proliferative glomerulonephritis within the higher.
The type of renal biopsy?
1, open renal biopsy
Double says look straight into a renal biopsy under, this method is small, the success rate can be drawn the blindness of 100% and can much place materials; But its creation, incidence rate of postoperative complications were can amount to 5%-10%.
2, percutaneous renal biopsy
"Renal biopsy, with renal biopsy back through the skin puncture point selected Pierce the lower pole of the materials. Renal biopsy is the most popular at home and abroad of renal biopsies method.
3, by intravenous biopsy
This method advantage is even if hemorrhage occurs, but also can limit in the kidney, the blood still flows into the blood circulating. Renal bulk is small, must avoid through cause renal renal weeks hematoma.
For nephrotic syndrome is effective method is to use the immune inhibitors of anti-inflammatory, reduce inflammation sex reaction at the same time the traditional Chinese medicine with the permeability therapy repair the damaged kidney function cell, make its restore function, achieve complete the objective of treatment!