Creatinine is a waste product produced by muscles, and it will be excreted by kidney. Once kidney is damaged, the glomerular filtration rate will decline, which is unable to excrete creatinine and other toxins, so the kidney function becomes worse and worse and finally Renal Failure or Uremia appear. We must take actions to lower creatinine with renal failure to stop further kidney damage.
At stage 1 and stage 2, the illness condition is not very severe, and it is comparatively easy to get the disease reversed. So patients should take actions in time, in case delay the illness condition. Once the disease develops into Renal Failure or Uremia, that means the condition is very severe and it is difficult to get the disease reversed, for little kidney function has been left, however, it is not impossible. If you still have some certain volume of urine and the bloodstream, of course, you need to do the checks to know how much kidney function is left, there will have the possibility to control your disease and avoid dialysis or a kidney transplant.
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