Children of nephrotic syndrome is proteinuria (24-hour urinary protein more
than 3.5 g) tall lipemia and different level of clinical syndrome features.
Common causes of glomerular disease by (such as primary glomerular inflammation,
glomerular focal sclerosis, etc), secondary glomerulonephritis (such as diabetic
nephropathy with lupus kidney disease, etc) and secondary infection (such as
bacteria, viruses, etc), the circulation system disease, drug poisoning cause.
Children early basement membrane lesions nephrotic syndrome is lighter, along
with lesions gradually progress, a lot of protein urine from the bodies, which
was reduced plasma protein important reasons. The fall in the levels of plasma
protein, especially the albumin significantly, cause plasma colloid osmotic
pressure drop, prompted the blood vessels in the blood vessels to the liquid,
cause tissue edema and effective capacity drops of blood. The children produced
nephrotic syndrome hyperlipidemia mechanism is not very clear.
Before the onset of the children often upper respiratory tract infection
history, mild edema only performance in the morning, eyelid edema, the person
that weigh the whole body, pitting oedema scrotal edema performance light,
severe swelling have ascites and chest water, the children often tired,
anorexia, WeiMi spirit, pale face wait for a symptom, the children immune
function is low, so often have infection, if not timely treatment can be
combined with hypovolemic shock, electrolyte imbalance vascular blockage and
acute renal failure, etc. Available adrenal cortical hormone and combining
traditional treatment.
The upper respiratory tract infection is inducement
Children's respiratory infections, such as colds, tonsillitis, acute
pharyngitis, if not to the timely and effective control of infection, in 1 ~ 4
weeks after may induce nephrotic syndrome. In general, children nephrotic
syndrome have early signs of infection, its outstanding characteristic is 3 tall
one low, namely high dropsy, high protein, high cholesterol and hypoalbuminemia.
Tiny disease degeneration nephrotic syndrome in age of onset two to six years
old children, and boy more than girls, extremely easy recurrence and delay, the
course of a long.
Little children because physique weaker, than normal immune cells less
people, the immune function is not strong, so the immune cells not only
sometimes devour the bacteria, but leave the bacteria inclusive up, the body of
germs and bacteria itself with antibody into a kind of immune complex, with
blood circulation, the kidney, the sedimentary glomerular basement membrane to,
so as to have a kidney damage, make a loss of protein, eventually leading to the
nephrotic syndrome.
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