Creatinine (Cr) is a muscle in the human body metabolism product, creatinine divided into serum creatinine and urine creatinine: normal serum creatinine in 53-140 μ moI/L; While urinary creatinine mainly from blood after glomerular filtration urine after serum creatinine. [reference] 8.4-3.25 1 mmol / 24-hour urine or 40 mg/dl to 130 mg/dl is normal. At the meat food intake are stable. The body's muscles metabolism and no big changes, the generation of creatinine is constant.
Creatinine is small molecules, but through the glomerular filtration, in the renal tube rarely absorption, the body produces daily serum creatinine, almost all with the urine, general from urine output effect. Kidney is not full-time, creatinine accumulation in the body be harmful to human body of toxins. The plasma creatinine normal limits for 100 micro Moore/liters. When the acute and chronic glomerulonephritis, glomerular filtration function to drop, creatinine increases.
Glomerular filtration rate down to normal 1/3, creatinine just increased dramatically. That means, for human kidney metabolic ability, when kidney damage is lighter when people feel not obvious discomfort, so a lot of people when appear truly nausea, vomiting, dizziness, in fact kidney has badly damaged, this time the serum creatinine also began to rise significantly.
For treatment in serum creatinine high, that of traditional treatment is only drop blood creatinine, and not to repair the basement membrane, this is the serum creatinine won't drop, even drop, it is temporary. As long as the damaged basement membrane after repair, change the kidney structure, expanded the glomerular filtration area, creatinine will gradually declined, but it needs a process, this time must prevent a cold, diet and emotional, don't tired, control blood pressure, blood sugar and other factors, protect renal function. As long as pay attention to it, the blood creatinine will fall down.
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