The human body renal reserve capacity, the person's kidney more than 75% of
the kidney unit does not work properly, creatinine high symptoms will be
revealed. That is, man's kidney hurt haven't reached the level, creatinine still
is normal. So in the kidney damage in the later stage of the serum creatinine
can have the clinical significance.
Creatinine is one of the body's metabolism product, and the main creatine
generation. Creatine can for our body muscle activities with energy. As long as
muscle activity will consume energy generation creatinine. But creatinine
constantly produce, the excessive accumulation in the body of the body to
produce poisonous effect. By constantly need glomerular filtration urine from
the body from the bodies.
When normal renal function, creatinine glomerular filter from urine from the
tossed out. Renal damage, creatinine from kidney row not to go out, but after
intestinal waste eliminated from the body. Normally produced in the body of the
speed of 1 serum creatinine mg/minutes, glomerular also at the same speed put it
cleared away. When kidney function decline to certain degree, the blood
creatinine can rise, but when compensatory mechanism normal renal function,
blood creatinine increased also can appear.
When left normal renal function of the three points at that time, the kidney
compensatory, blood creatinine increased only, so blood creatinine and not
sensitivity of glomerular filtration function index. The normal serum creatinine
is 40-120 umol/L, muscle atrophy, thin body, factors such as pregnancy can make
creatinine slightly low. Opinion, creatinine indicators and was not accurate in
reflecting the stand or fall of renal function.
Renal failure treatment including the following aspects:
(1) for renal failure causes treatment, such as expansion before correcting
kidney factors, remove after kidney obstruction factors, renal failure
accelerated sex or other severe glomerulonephritis impact will be awarded with
hormone effect, allergic interstitial nephritis should stop immediately, give
allergy medications, etc.
(2) less urine period, fluid intake to measured for into the for the
principle.
(3) correct high potassium hematic disease and acidosis.
(4) the renal failure should be started as soon as possible dialysis therapy,
dehydration, remove toxin and correct electrolyte and acid-base disorders
disorder of function, make renal failure patients spend less urine period of
difficulties. More strict monitoring urine period water, electrolyte balance in
case died from dehydration and electrolytes disturbance. Renal failure recovery
strengthening nutrition, rest and avoid to use renal toxicity drug are very
important.
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